Write full names (“levator palpebrae superioris,” not “LPS”; “superior orbital fissure,” not “SOF”). Cranial nerves may be written as CN III or oculomotor nerve.
“LR6, SO4, AO3” — lateral rectus = CN VI, superior oblique = CN IV, all others (including LPS) = CN III.
Lacrimal gland: CN VII → greater petrosal nerve → pterygopalatine ganglion → zygomatic nerve (V2) → lacrimal nerve (V1) → gland. The lesser petrosal nerve is CN IX → otic ganglion → parotid.
Every orbital artery is a branch of the ophthalmic artery (from the internal carotid artery), and each travels with the nerve of the same name.
Only parasympathetic fibers synapse in the ciliary ganglion. Short ciliary nerves come from the ganglion; long ciliary nerves come from the nasociliary nerve and bypass it.
Light reflex: afferent CN II, efferent CN III. Corneal reflex: afferent CN V1 (nasociliary), efferent CN VII (bilateral).
H-test: ABduct → test the Recti · ADduct → test the Obliques.
Infratrochlear (V1, nasociliary) ≠ infraorbital (V2, orbital floor).
The orbital apex is posteromedial — the optic canal is in the lesser wing of the sphenoid.
2 · Bony Orbit, Walls & Openings
Seven bones form the orbit: frontal, zygomatic, maxilla, lacrimal, ethmoid, sphenoid, palatine. It’s a four-sided pyramid: broad base at the orbital margin, apex at the optic canal (posteromedial). The eyeball fills only the anterior half; the posterior half is orbital fat, extraocular muscles, nerves and vessels. The periorbita is the periosteum lining the orbit.
Right orbit, coronal schematic (medial side toward the nose on the right of the figure). Red = thin walls prone to blowout.
Opening
Location
Contents
Optic canal
Lesser wing of sphenoid (apex)
CN II + ophthalmic artery
Superior orbital fissure
Between lesser & greater wings of sphenoid
CN III, IV, VI · frontal, lacrimal, nasociliary nerves (V1) · superior ophthalmic vein
Seven voluntary muscles: 4 recti, 2 obliques, and levator palpebrae superioris. All but the inferior oblique arise near the orbital apex; the inferior oblique arises from the anterior orbital floor.
Muscle
Primary
Secondary
Nerve
H-test
Medial rectus
Adduction
—
CN III
—
Lateral rectus
Abduction
—
CN VI
—
Superior rectus
Elevation
Adduction, intorsion
CN III
Abduct → look up
Inferior rectus
Depression
Adduction, extorsion
CN III
Abduct → look down
Superior oblique (tendon through the trochlea)
Depression
Abduction, intorsion
CN IV
Adduct → look down
Inferior oblique
Elevation
Abduction, extorsion
CN III
Adduct → look up
Levator palpebrae superioris
Elevates the upper eyelid (lies above superior rectus — a lab landmark)
CN III
—
The H-test for one eye. Left bar = eye turned OUT (temporal); right bar = eye turned IN (nasal). Obliques act opposite to their names: inferior oblique elevates, superior oblique depresses.
Pairing rules
SR + IR both adduct
SO + IO both abduct
SR + SO both intort — “Superiors INtort”
IR + IO both extort
Why secondary actions?
The orbital axis angles posteromedially while the optical axis points straight ahead, so SR, IR and the obliques pull at an angle. Moving the eye into abduction or adduction lines a muscle up with its pull — that’s the H-test.
Conjugate gaze: looking to the right = right lateral rectus (CN VI) + left medial rectus (CN III).
5 · Palsies & the Eyelid
CN III
CN IV
CN VI
Lost
SR, IR, MR, IO, LPS + sphincter pupillae + ciliary
Superior oblique
Lateral rectus
Eye position
Down and out (SO + LR unopposed)
Slightly up
Turned in
Lid / pupil
Complete ptosis, dilated pupil, no accommodation
Normal
Normal
Diplopia
Multiple directions
Vertical, worst looking down and in (reading, stairs); head tilts away
Horizontal, worst looking out toward the lesion
Lab landmark
Branches to SR/LPS above and MR/IR/IO below
Tiny nerve ending in superior oblique
On the inner surface of lateral rectus
Eyelid openers vs closer
LPS (skeletal)←CN III
Superior tarsal muscle (smooth)←Sympathetics
Orbicularis oculi (closes)←CN VII
Layers front → back: skin → thin subcutaneous tissue → orbicularis oculi → orbital septum/tarsus → conjunctiva.
Ptosis: CN III vs Horner
CN III
Horner
Ptosis
Complete (LPS)
Mild (superior tarsal)
Pupil
Dilated
Small (miosis)
Other
Down and out
Anhidrosis
6 · CN V1 in the Orbit — “NFL”
CN V1 (ophthalmic division) — enters through the superior orbital fissure
N · Nasociliary nerve
Crosses over CN II toward the medial wall
Anterior ethmoidal nerve → anterior ethmoidal foramen → ends as external nasal nerve (tip of nose)
Supratrochlear nerve (medial) → above the trochlea → medial forehead
L · Lacrimal nerve
Along the upper lateral wall
Sensory: lateral upper lid, conjunctiva, gland region
Receives the communicating branch from the zygomatic nerve (V2) → carries postganglionic secretomotor fibers to the lacrimal gland
Lab landmark: find the lacrimal gland first
Hutchinson sign
Herpes zoster vesicles on the tip of the nose = external nasal branch of the nasociliary nerve → high risk of ocular involvement, because the nasociliary nerve also supplies the eye (long ciliary nerves).
CN V2 in the orbit: the zygomatic nerve (→ zygomaticofacial + zygomaticotemporal) and infraorbital nerve enter through the inferior orbital fissure; the infraorbital nerve runs in the floor and exits the infraorbital foramen.
7 · Ciliary Ganglion & Ciliary Nerves
A tiny parasympathetic ganglion in the posterior orbit, lateral to the optic nerve. One of the four head ganglia — “COPS”: Ciliary, Otic, Pterygopalatine, Submandibular.
Superior ophthalmic vein → superior orbital fissure. Inferior ophthalmic vein → inferior orbital fissure. Both connect to the cavernous sinus — valveless, so infection can spread backward.
Not in the orbit
The facial artery is an external carotid branch on the face — it does not supply the orbit’s contents. Orbit = ophthalmic artery (internal carotid system).
9 · Commonly Confused
Pair
Difference
Supratrochlear vs infratrochlear
Above the trochlea = frontal nerve branch · below the trochlea = nasociliary branch (both V1)
Supraorbital vs infraorbital
Supraorbital = V1 (frontal nerve), frontal bone notch · infraorbital = V2, orbital floor → maxilla
Long vs short ciliary
Long = nasociliary, bypass ganglion · short = from the ganglion
Greater vs lesser petrosal
Greater = CN VII → pterygopalatine → lacrimal gland · lesser = CN IX → otic → parotid
Superior vs inferior ophthalmic vein
Superior orbital fissure vs inferior orbital fissure
Inferior rectus paralyzed vs trapped
Paralyzed → can’t look down · trapped in floor fracture → tethered, can’t look up